Mapi Publications

2017. Berger T et al. – New insights into the burden and costs of multiple sclerosis in Europe: Results for Austria

 

Berger T, Kobelt G, Berg J, Capsa D, Gannedahl M; European Multiple Sclerosis Platform. New insights into the burden and costs of multiple sclerosis in Europe: Results for Austria. Mult Scler. 2017 Aug;23(2_suppl):17-28.

https://www.ncbi.nlm.nih.gov/pubmed/28643599

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Abstract

INTRODUCTION: In order to estimate the value of interventions in multiple sclerosis (MS) - where lifetime costs and outcomes cannot be observed - outcome data have to be combined with costs. This requires that cost data be regularly updated.

OBJECTIVES AND METHODS: This study is part of a cross-sectional retrospective study in 16 countries collecting data on resource consumption and work capacity, health-related quality of life (HRQoL) and prevalent symptoms for patients with MS. Descriptive analyses are presented by level of severity, from the societal perspective, in EUR 2015.

RESULTS: A total of 516 patients (mean age, 53 years) participated in Austria; 72% were below retirement age, and of these, 46% were employed. Employment was related to disability, and MS affected productivity at work for 77% of those working. Overall, 94% and 67% of patients experienced fatigue and cognition as a problem. Mean utility and total annual costs were 0.778 and 25,100€ at Expanded Disability Status Scale (EDSS) 0-3, 0.579 and 44,100€ at EDSS 4-6.5, and 0.244 and 73,800€ at EDSS 7-9. The mean cost of a relapse was estimated at 2563€.

CONCLUSION: This study illustrates the burden of MS on Austrian patients and provides current data on MS that are important for development of health policies.